Casein Kinase Iε Mouse, Unlabeled, Clone: 1, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 610446

Catalog No. BDB610446

Description

Casein Kinase I? (CKIε) is a product of a family of proteins involved in the regulation of various cytoplasmic and nuclear processes including DNA replication and repair. CKIε is a 47.3kDa serine/threonine kinase that plays a role similar to previously described CKI isoforms. It phosphorylates known CKI substrates, including a CKI-specific peptide. In addition, it is inhibited by CKI-7, an inhibitor of other CKI isoforms. CKIε contains a core kinase domain of 285 amino acids which is 53-98% identical to other isoforms and is most similiar in structure to CKIδ. Since various human and yeast CKI proteins exhibit both sequence and functional similarities, CKIε may be involved in mammalian DNA metabolism.

Immunofluorescence, Immunoprecipitation, Western Blotting

Specifications

• Antigen: Casein Kinase Iε
• Clone: 1
• Conjugate: Unconjugated
• Format: Affinity Purified
• Immunogen: Human Casein Kinase Iε aa. 248-414
• Quantity: 150μg
• Research Discipline: Cell Biology
• Primary or Secondary: Primary
• Target Species: Canine, Chicken, Human, Murine, Rat

• Applications: Western Blot
• Concentration: 250μg/mL
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Host Species: Murine
• Isotype: IgG₁
• Regulatory Status: RUO
• Storage Requirements: Store undiluted at -20°C.
• Monoclonal or Polyclonal: Monoclonal

For Research Use Only.