Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Casein Kinase IIα/α Mouse, Unlabeled, Clone: 31, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 611611

 View more versions of this product

Catalog No. BDB611611

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.



Casein kinase II (CKII, CK2) is a pleiotropic, ubiquitous, and constitutively active Ser/Thr kinase that utilizes both ATP and GTP as phosphoryl donors to catalyze the phosphorylation of numerous protein substrates. It has been implicated in DNA replication, control of metabolism, and regulation of transcription and translation. CKII is a messenger independent kinase due to the fact that its activity is not affected by factors that regulate other protein kinases (e.g. cAMP, Ca2+, diacylglycerol). It is composed of two catalytic (α and α′) subunits and two regulatory (β) subunits. The β subunits stabilize the holoenzyme and enhance the activity of the α subunits. Although the enzyme exists as a tetramer, the free α/α′ subunits are catalytically active by themselves and are present in cells under some conditions. The α and α′ subunits (85% homologous) are encoded by distinct genes and have been detected in multiple species including human, bovine, and avian. CKII is found primarily in the nucleus in dividing cells, but can be detected in the cytoplasm in quiescent cells. Thus, CKII activity is required for cell cycle progression and other essential signal transduction events.

Host Species: Mouse
Clone: 31
Isotype: IgG1
Species Reactivity [for Features Main]: Rat
Immunogen: Rat Casein Kinase II α aa. 1-123

Immunofluorescence, Western Blotting



Casein Kinase IIα/α
Human, Murine, Rat
Western Blot
Affinity Purified
Rat Casein Kinase II α aa. 1-123
Cell Biology
Product Certifications


Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only.