caspase 9, apoptosis-related cysteine peptidase, Mouse, Clone: 4F12-G6, Abnova™

Catalog No.	Quantity
89-000-557	100 μg

Catalog No. 89-000-557 Supplier Abnova Corporation Supplier No. H00000842M02

Description

Mouse monoclonal antibody raised against a full-length recombinant CASP9.

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq

Sequence: MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS

Specifications

• Antigen: caspase 9, apoptosis-related cysteine peptidase
• Applications: ELISA, In situ PLA, Western Blot
• Classification: Monoclonal
• Clone: 4F12-G6
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full length recombinant CASP9.
• Formulation: PBS with no preservative; pH 7.4
• Gene: CASP9
• Gene Accession No.: BC002452
• Gene Alias: APAF-3/APAF3/CASPASE-9c/ICE-LAP6/MCH6
• Gene Symbols: CASP9
• Host Species: Mouse
• Immunogen: CASP9 (AAH02452.1, 1 a.a. ∼ 416 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Apoptosis
• Whole Molecule: Yes
• Primary or Secondary: Primary
• Gene ID (Entrez): 842
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Isotype: IgG1 κ