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anti-Caspase 7 (Mch 3), Clone: 7CSP03, same as 13.1.97, Epredia™ LabVision
Shop All Epredia ProductsDescription
Caspase 7 functions as an effector caspase that cleaves downstream substrates responsible for producing the morphological and biochemical changes associated with apoptosis. The alpha form of caspase 7 is 303 amino acids and gets cleaved upon activatiuon to 20 and 12kDa subunits. A 253 aa beta form, presumably a result of alternative splicing, lacks the cysteine protease active site (QACRG) and may function as a dominant negative regulator of apoptosis.
Host Species: Mouse
Clone: 7CSP03; same as 13.1.97
Isotype: IgG1/κ
Cross Reactivity: Human and Mouse. Others-not tested.
Epitope: Not determined
Immunogen: Recombinant full length human Caspase 7 protein.
Molecular Weight: 35kDa (Proform) and 20kDa (Cleavage fragments)
Positive Control: Jurkat cells. Tonsil.
Cellular Localization: Cytoplasmic
Immunohistochemistry (Formalin/Paraffin), Western Blotting
Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly
Specifications
Specifications
| Antigen | Caspase 7 (Mch 3) Ab-3 |
| Classification | Monoclonal |
| Concentration | 200μg/mL |
| Conjugate | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant full length human Caspase 7 protein. |
| Purification Method | Jurkat cells, tonsil |
| Quantity | 1 mL |
| Primary or Secondary | Primary |
| Target Species | Human, Mouse |
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