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CASR, Mouse, Clone: 3F12, Abnova™

Catalog No. 89016438 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-016-438 100 μg
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Catalog No. 89-016-438 Supplier Abnova Corporation Supplier No. H00000846M01
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Description

Mouse monoclonal antibody raised against a partial recombinant CASR.

The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq

Sequence: GPDQRAQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRYNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKI

Specifications

Antigen CASR
Applications ELISA
Classification Monoclonal
Clone 3F12
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a partial recombinant CASR.
Formulation PBS with no preservative; pH 7.4
Gene CASR
Gene Accession No. NM_000388
Gene Alias CAR/FHH/FIH/GPRC2A/HHC/HHC1/MGC138441/NSHPT/PCAR1
Gene Symbols CASR
Host Species Mouse
Immunogen CASR (NP_000379, 21 a.a. ∼ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 846
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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