Cathepsin V Mouse anti-Human, Clone: 182021, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523928
In direct ELISAs and Western blots, no cross-reactivity with recombit human Cathepsin B, C, F, L, O, S, or Z is observed. This antibody specifically identifies the pro form but not the active form of Cathepsin V in Western blots. Reconstitute at 0.5 mg/mL in sterile PBS.Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.
|PBS with 5% trehalose and No Preservative|
|Cathepsin L2, Cathepsin U, Cathepsin V, CTSV, CATL2, CTSL2, CTSU, UNQ268, PRO305, CATL2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunoprecipitation, Western Blot|
|Mouse myeloma cell line NS0-derived recombit human Cathepsin V Val18-Val334|
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