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Cathepsin V Mouse anti-Human, Clone: 182021, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523928

Catalog No. PIMA523928


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Description

Description

In direct ELISAs and Western blots, no cross-reactivity with recombit human Cathepsin B, C, F, L, O, S, or Z is observed. This antibody specifically identifies the pro form but not the active form of Cathepsin V in Western blots. Reconstitute at 0.5 mg/mL in sterile PBS.

Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.
Specifications

Specifications

Cathepsin V
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
O60911
Cathepsin L2, Cathepsin U, Cathepsin V, CTSV, CATL2, CTSL2, CTSU, UNQ268, PRO305, CATL2
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
1515
Immunoprecipitation, Western Blot
182021
Unconjugated
CTSV
Lyophilized
CTSV
Mouse myeloma cell line NS0-derived recombit human Cathepsin V Val18-Val334
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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