CBL (M01), Mouse anti-Human, Clone: 6D12, Abnova™

Catalog No.	Quantity
89-016-464	200 μL

Catalog No. 89-016-464 Supplier Abnova Corporation Supplier No. H00000867M01C

Description

Mouse monoclonal antibody raised against a partial recombinant CBL.

The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq

Sequence: NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSER

Specifications

• Antigen: CBL
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 6D12
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a partial recombinant CBL.
• Formulation: tissue culture supernatant with no preservative
• Gene: CBL
• Gene Accession No.: NM_005188
• Gene Alias: C-CBL/CBL2/RNF55
• Gene Symbols: CBL
• Host Species: Mouse
• Immunogen: CBL (NP_005179, 736 a.a. ∼ 835 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 200 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 867
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ