CBS, Mouse, Clone: 3D10, Abnova™
Mouse monoclonal antibody raised against a partial recombinant CBS.
Manufacturer: Abnova Corporation H00000875M02
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. [provided by RefSeqSequence: MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPSRCTWQLGRPASESPHHHTAPAKSPKILPDILKKIGDTPMVRINKIGKKFG
|PBS with no preservative; pH 7.4|
|Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|ELISA, Immunofluorescence, Immunoprecipitation, Western Blot|
|Mouse monoclonal antibody raised against a partial recombinant CBS.|
|CBS (NP_000062, 1 a.a. ∼ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
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