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CCDC141 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA521169

Catalog No. PIPA521169


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Description

Description

A suggested positive control is SK-N-SH cell lysate. PA5-21169 can be used with blocking peptide PEP-1283.

Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development.
Specifications

Specifications

CCDC141
Polyclonal
Unconjugated
CCDC141
Liquid
CCDC141
An 18 amino acid peptide near the amino terminus of human CCDC141.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q6ZP82
CAMDI; coiled-coil domain-containing protein 141; coiled-coil protein associated with myosin II and DISC1
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
285025, 545428
Documents
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