Learn More
CCR10 Mouse anti-Human, APC, Clone: 1B5, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 564771
Description
The 1B5 monoclonal antibody specifically binds to CCR10 (CC-chemokine receptor 10). CCR10 is a seven transmembrane domain G-protein-coupled receptor that is also known as GPR-2 (G-protein coupled receptor 2). CCR10 is expressed by cells that mediate epithelial immunity including a small subset of T memory cells, IgA-secreting B cells, dermal endothelial cells and fibroblasts. It is also expressed on EBV-immortalized B cells. Chemokine CCL27 and CCL28 are the ligands for CCR10. CCR10 reportedly not only functions in regulating the homing and function of cells that mediate epithelial immunity. It may also regulate the epithelial localization, survival, and proliferation of tumor cells and facilitate their evasion from immune surveillance.
Specifications
CCR10 | |
Monoclonal | |
0.2mg/mL | |
C-C CKR-10, C-C CKR-10, G-protein coupled receptor 2, CCR-10, GPR2 | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG2a κ |
Flow Cytometry | |
1B5 | |
APC | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Human CCR10 Transfected Cell Line | |
25 μg | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.