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CCR10 Mouse anti-Human, PE, Clone: 1B5, BD

Catalog No. BDB563656 Shop All BD Biosciences Products
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BDB563656 25 μg
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Catalog No. BDB563656 Supplier BD Biosciences Supplier No. 563656
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Description

Mouse Monoclonal Antibody

The 1B5 monoclonal antibody specifically binds to CCR10 (CC-chemokine receptor 10). CCR10 is a seven transmembrane domain G-protein-coupled receptor that is also known as GPR-2 (G-protein coupled receptor 2). CCR10 is expressed by cells that mediate epithelial immunity including a small subset of T memory cells, IgA-secreting B cells, dermal endothelial cells and fibroblasts. It is also expressed on EBV-immortalized B cells. Chemokine CCL27and CCL28 are the ligands for CCR10. CCR10 reportedly not only functions in regulating the homing and function of cells that mediate epithelial immunity. It may also regulate the epithelial localization, survival, and proliferation of tumor cells and facilitate their evasion from immune surveillance.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CCR10
Applications Flow Cytometry
Classification Monoclonal
Clone 1B5
Concentration 0.2mg/mL
Conjugate PE
Description C-C CKR-10, C-C CKR-10, G-protein coupled receptor 2, CCR-10, GPR2
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human CCR10 Transfected Cell Line
Purification Method Affinity Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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