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CCRL2 Rat anti-Mouse, PE, Clone: BZ2E3, BD

Catalog No. BDB564946 Shop All BD Biosciences Products
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BDB564946 50 μg
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Catalog No. BDB564946 Supplier BD Biosciences Supplier No. 564946
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Description

Rat Monoclonal Antibody

The BZ2E3 monoclonal antibody specifically binds to CCRL2 (C-C chemokine receptor-like 2) which is also known as Lipopolysaccharide-inducible C-C chemokine receptor (L-CCR/Lccr). CCRL2 is a chemokine receptor-like, 7-transmembrane protein that can bind CCL19 or the nonchemokine chemoattractant, chemerin/RARRES2. CCRL2 is expressed by a variety of cell types including mast cells, macrophages and some endothelial cells. CCRL2 appears to play various roles in regulating chemokine activities, e.g., by binding and internalizing excess local levels of the CCL19 /MIP-3β chemokine. Alternatively, endothelial cell-expressed CCRL2 can bind and present the chemerin/RARRES2 chemoattractant to lymphoid cells that express the functional signaling receptor, CMKLR1, and promote their adhesion.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CCRL2
Applications Flow Cytometry
Classification Monoclonal
Clone BZ2E3
Concentration 0.2mg/mL
Conjugate PE
Description C-C chemokine receptor-like 2; L-CCR; Lccr; Cmkbr1l2; Ackr5
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse CCRL2 Peptide
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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