CD100 (Sema4D) Mouse anti-Human, Alexa Fluor 647, Clone: A8, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564873
The A8 monoclonal antibody specifically binds to CD100 which is also known as Semaphorin-4D (SEMA4D). CD100 is a 150 kDa type I transmembrane glycoprotein that belongs to the semaphorin family. CD100 is widely expressed in the nervous and immune systems. Although it is expressed on T cells, its expression is significantly upregulated on activated T cells. It is also expressed on NK cells, B cells, and monocytes. CD100 is an adhesion molecule that functions as a signaling molecule which plays a role in lymphocyte activation. CD100 interaction with CD72 enhances B cell signaling and ultimately promotes B cell activation and survival.
|Semaphorin-4D ; SEMA4D; SEM4D; SEMAJ; GR3; C9orf164|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Alexa Fluor 647|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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