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Description
The A8 monoclonal antibody specifically binds to CD100 which is also known as Semaphorin-4D (SEMA4D). CD100 is a 150 kDa type I transmembrane glycoprotein that belongs to the semaphorin family. CD100 is widely expressed in the nervous and immune systems. Although it is expressed on T cells, its expression is significantly upregulated on activated T cells. It is also expressed on NK cells, B cells, and monocytes. CD100 is an adhesion molecule that functions as a signaling molecule which plays a role in lymphocyte activation. CD100 interaction with CD72 enhances B cell signaling and ultimately promotes B cell activation and survival.
Specifications
Specifications
| Antigen | CD100 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | A8 |
| Conjugate | Alexa Fluor 647 |
| Description | Semaphorin-4D ; SEMA4D; SEM4D; SEMAJ; GR3; C9orf164 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
| Quantity | 50 Tests |
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