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CD101 (Igsf2) Rat anti-Mouse, Alexa Fluor 647, Clone: 307707, BD

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BDB564473 50 Tests
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Catalog No. BDB564473 Supplier BD Biosciences Supplier No. 564473
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Description

Rat Monoclonal Antibody

The 307707 monoclonal antibody specifically binds to CD101 which is also known as Igsf2 (Immunoglobulin superfamily member 2). CD101 is a type I transmembrane glycoprotein that belongs to the EWI (sharing a conserved glutamine-tryptophan-isoleucine motif) family within the Ig superfamily. CD101 is expressed on monocytes, granulocytes, dendritic cells, Langerhans cells and activated T cells. CD101 reportedly plays a role in the regulation of T cell activation. CD101 was found to be expressed on a subset of CD25+Foxp3+ T regulatory cells that showed higher suppressive properties in vitro and in vivo. Polymorphisms in Cd101 are associated with type I diabetes susceptibility.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD101
Applications Flow Cytometry
Classification Monoclonal
Clone 307707
Conjugate Alexa Fluor 647
Description Igsf2; EWI-101; Gm1016; Gm734
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse CD101 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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