CD101 (Igsf2) Rat anti-Mouse, Alexa Fluor 647, Clone: 307707, BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 564473
The 307707 monoclonal antibody specifically binds to CD101 which is also known as Igsf2 (Immunoglobulin superfamily member 2). CD101 is a type I transmembrane glycoprotein that belongs to the EWI (sharing a conserved glutamine-tryptophan-isoleucine motif) family within the Ig superfamily. CD101 is expressed on monocytes, granulocytes, dendritic cells, Langerhans cells and activated T cells. CD101 reportedly plays a role in the regulation of T cell activation. CD101 was found to be expressed on a subset of CD25+Foxp3+ T regulatory cells that showed higher suppressive properties in vitro and in vivo. Polymorphisms in Cd101 are associated with type I diabetes susceptibility.
|Igsf2; EWI-101; Gm1016; Gm734|
|Mouse CD101 Recombinant Protein|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
|Alexa Fluor 647|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok