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CD101 (Igsf2) Rat anti-Mouse, Alexa Fluor 647, Clone: 307707, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 564473

Catalog No. BDB564473

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The 307707 monoclonal antibody specifically binds to CD101 which is also known as Igsf2 (Immunoglobulin superfamily member 2). CD101 is a type I transmembrane glycoprotein that belongs to the EWI (sharing a conserved glutamine-tryptophan-isoleucine motif) family within the Ig superfamily. CD101 is expressed on monocytes, granulocytes, dendritic cells, Langerhans cells and activated T cells. CD101 reportedly plays a role in the regulation of T cell activation. CD101 was found to be expressed on a subset of CD25+Foxp3+ T regulatory cells that showed higher suppressive properties in vitro and in vivo. Polymorphisms in Cd101 are associated with type I diabetes susceptibility.



Igsf2; EWI-101; Gm1016; Gm734
Affinity Purified
Mouse CD101 Recombinant Protein
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Flow Cytometry
Alexa Fluor 647
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IgG2a, κ
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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