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CD103 Rat anti-Mouse, NA/LE, Unlabeled, Clone: M290, BD

Catalog No. BDB553699 Shop All BD Biosciences Products
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BDB553699 0.5 mg
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Catalog No. BDB553699 Supplier BD Biosciences Supplier No. 553699
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Description

Rat Monoclonal Antibody

The M290 antibody specifically binds to CD103, the α chain of αIELβ7 integrin. CD103 has a unique and fairly restricted tissue distribution. It is expressed on almost all intestinal intraepithelial lymphocytes (IEL), on dendritic epidermal T cells (DEC), on subpopulations of peripheral T cells, and on distinct subsets of fetal, neonatal, and adult thymocytes. E-cadherin is the epithelial-cell ligand for αIELβ7 integrin. The ordered expression of αIEL during thymocyte development (which occurs under the influence of the thymic epithelium), the high level of expression of ααIELβ7-mediated adhesion in in vitro assays.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD103
Applications Flow Cytometry
Classification Monoclonal
Clone M290
Concentration 1.0mg/mL
Conjugate Unconjugated
Description Itgae; Integrin alpha-E; αE; alpha-E1; ITAE; Integrin αIEL chain; aM290
Formulation No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species Rat
Immunogen Mouse mammary tumor cells
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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For Research Use Only.

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