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CD105 Rat anti-Mouse, BB515, Clone: MJ7/18, BD

Catalog No. BDB564744 Shop All BD Biosciences Products
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BDB564744 50 μg
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Catalog No. BDB564744 Supplier BD Biosciences Supplier No. 564744

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Description

Rat Monoclonal Antibody

The MJ7/18 monoclonal antibody specifically binds to mouse CD105 (also known as endoglin) which is a homodimer of 90-kDa subunits and is predominantly expressed on vascular endothelial cells. High levels of mouse endoglin mRNA have been reported to be detectable in the ovary, uterus, NCTC-2071 fibroblasts, and to a lesser extent, in heart, muscle and stromal cells in connective tissue of various organs. Endoglin has been reported to play an essential role in embryonic angiogenesis. Both mouse and human endoglin display strong amino-acid sequence homology to the transmembrane and cytoplasmic regions of the type III TGF-ß receptor.

The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (eg, 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD105
Applications Flow Cytometry
Classification Monoclonal
Clone MJ7/18
Concentration 0.2mg/mL
Conjugate Brilliant Blue 515 (BB515)
Description Endoglin; Edg; EGLN; Eng; MJ7/18 antigen; S-endoglin
Formulation Aqueous buffered solution containing ≤0.09% sodium azide
Host Species Rat
Immunogen Mouse skin (inflamed)
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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