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CD105 Rat anti-Mouse, BB515, Clone: MJ7/18, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 564744

Catalog No. BDB564744


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Description

Description

The MJ7/18 monoclonal antibody specifically binds to mouse CD105 (also known as endoglin) which is a homodimer of 90-kDa subunits and is predominantly expressed on vascular endothelial cells. High levels of mouse endoglin mRNA have been reported to be detectable in the ovary, uterus, NCTC-2071 fibroblasts, and to a lesser extent, in heart, muscle and stromal cells in connective tissue of various organs. Endoglin has been reported to play an essential role in embryonic angiogenesis. Both mouse and human endoglin display strong amino-acid sequence homology to the transmembrane and cytoplasmic regions of the type III TGF-ß receptor.

The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (eg, 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

Specifications

Specifications

CD105
MJ7/18
BB515
Aqueous buffered solution containing ≤0.09% sodium azide
Rat
IgG2a, κ
RUO
Primary
Murine
Flow Cytometry
0.2mg/mL
Endoglin; Edg; EGLN; Eng; MJ7/18 antigen; S-endoglin
Affinity purified
Mouse skin (inflamed)
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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