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Description
The MR106 antibody reacts with CD106, the ∽110 kDa transmembrane vascular cell adhesion molecule-1 (VCAM-1). Expression of CD106 on endothelial cells is induced by inflammatory cytokines and in certain pathologic conditions. In the rat bone marrow, CD106 has been reported to be expressed on dendritic cells and subsets of the myeloid lineage, but not detectable on peripheral leukocytes. CD106 has been reported to be a counter-receptor for VLA-4 ( α 4β 1 integrin) and α 4β 7 integrin, and it plays an important role in leukocyte extravasation, particularly at sites of inflammation.
Specifications
Specifications
| Antigen | CD106 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | MR106 |
| Concentration | 0.2mg/mL |
| Conjugate | PE |
| Description | VCAM-1 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Rat VCAM-1-transfected L5178Y Cells |
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