CD107a Rat anti-Mouse, FITC, Clone: 1D4B, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 553793

Catalog No. BDB553793

Description

The 1D4B antibody recognizes CD107a (Lysosome-Associated Membrane Protein 1, LAMP-1), one of the two major glycoproteins in lysosome membranes which are useful markers to distinguish lysosomes from other organelles. Mouse CD107a consists of a 40kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. Several lines of evidence suggest that cell-surface mouse and human LAMP-1 glycoproteins, the expression of which may correlate with malignant transformation, participate in intercellular adhesion and adhesion to extracellular matrix.

Host Species: Rat
Clone: 1D4B
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: Plasma membrane fraction of mouse embryo NIH 3T3 cell line

Intracellular Staining

Specifications

• Antigen: CD107a
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: LAMP-1; LGP-120; LGP-A; P2B
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 1D4B
• Conjugate: FITC
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Plasma membrane fraction of mouse embryo NIH 3T3 cell line
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG2a κ

For Research Use Only.