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Description
The 1D4B antibody recognizes CD107a (Lysosome-Associated Membrane Protein 1, LAMP-1), one of the two major glycoproteins in lysosome membranes which are useful markers to distinguish lysosomes from other organelles. Mouse CD107a consists of a 40kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. Several lines of evidence suggest that cell-surface mouse and human LAMP-1 glycoproteins, the expression of which may correlate with malignant transformation, participate in intercellular adhesion and adhesion to extracellular matrix.
Host Species: Rat
Clone: 1D4B
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: Plasma membrane fraction of mouse embryo NIH 3T3 cell line
Intracellular Staining
Specifications
Specifications
| Antigen | CD107a |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 1D4B |
| Concentration | 0.5mg/mL |
| Conjugate | FITC |
| Description | LAMP-1; LGP-120; LGP-A; P2B |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Plasma membrane fraction of mouse embryo NIH 3T3 cell line |
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For Research Use Only.
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