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CD110 Mouse anti-Human, PE, Clone: 1.6.1, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 562159
Description
The 1.6.1 monoclonal antibody specifically binds to the human Thrombopoietin Receptor (TPO-R) that is also known as the Myeloproliferative leukemia protein (c-Mpl) or CD110. CD110 is a type I transmembrane glycoprotein and a member of the hematopoietin receptor family. It is expressed on hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage and platelets. CD110 serves as a receptor for thrombopoietin. Upon binding of thrombopoietin to CD110, megakaryocyte proliferation and differentiation is induced, platelets are produced and stem cells are protected from apoptosis.
Specifications
| CD110 | |
| Monoclonal | |
| 0.2mg/mL | |
| C-MPL; MPL; MPLV; TPOR; Thrombopoietin receptor | |
| Mouse | |
| 0.1 mg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| 1.6.1 | |
| PE | |
| Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide. | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG2b κ |
Safety and Handling
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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