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CD110 Mouse anti-Human, PE, Clone: 1.6.1, BD

Catalog No. BDB562159 Shop All BD Biosciences Products
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Description

Mouse Monoclonal Antibody

The 1.6.1 monoclonal antibody specifically binds to the human Thrombopoietin Receptor (TPO-R) that is also known as the Myeloproliferative leukemia protein (c-Mpl) or CD110. CD110 is a type I transmembrane glycoprotein and a member of the hematopoietin receptor family. It is expressed on hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage and platelets. CD110 serves as a receptor for thrombopoietin. Upon binding of thrombopoietin to CD110, megakaryocyte proliferation and differentiation is induced, platelets are produced and stem cells are protected from apoptosis.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD110
Applications Flow Cytometry
Classification Monoclonal
Clone 1.6.1
Concentration 0.2mg/mL
Conjugate PE
Description C-MPL; MPL; MPLV; TPOR; Thrombopoietin receptor
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2b κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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