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CD117 Mouse anti-Human, APC, Clone: YB5.B8, BD

Catalog No. BDB561118 Shop All BD Biosciences Products
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25 μg
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BDB561118 25 μg
BDB550412 1 mg
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Catalog No. BDB561118 Supplier BD Biosciences Supplier No. 561118
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Description

Mouse Monoclonal Antibody

Recognizes CD117 (the C-Kit), a 145kDa cell-surface glycoprotein with tyrosine kinase activity. CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes. CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF). The interaction of c-kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development. The ability of YB5.B8 antibody to block the binding of c-kit ligand is still
controversial. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: YB5.B8
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD117
Applications Flow Cytometry
Classification Monoclonal
Clone YB5.B8
Concentration 0.2mg/mL
Conjugate APC
Description KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Acute myelocytic leukemia blasts
Purification Method Affinity Purified
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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