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Description
The 2E2 antibody recognizes the extracellular region of the 90 kDa alpha chain subunit of the mouse interferon- γreceptor (IFN- γR α ; aka , CD119). The functionally active-form of the mouse IFN- γreceptor consists of two (or more) subunits, with IFN- γγR α and IFN- γR β chains required for the transduction of biologic responses. IFN- γR α is expressed by a variety of cell lines and normal mouse cells (except mature erythrocytes) including T cells, B cells, NK cells, monocytes, neutrophils, fibroblasts, epithelial and endothelial cells. The 2E2 antibody is a non-neutralizing antibody; it does not block the binding of IFN- γto its receptor. The immunogen used to generate this hybridoma was a purified preparation of soluble recombinant mouse IFN- γR α chain protein.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Specifications
Specifications
| Antigen | CD119 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 2.00E+02 |
| Concentration | 0.5mg/mL |
| Conjugate | Biotin |
| Description | Ifngr1; IFN-γ Receptor α; IFN-gamma R alpha; Ifngr; INF-g Receptor; Cd119 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Hamster |
| Immunogen | Purified preparation of soluble recombinant mouse IFN-γRα chain protein |
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Safety and Handling
For Research Use Only.
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