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CD119 Rat anti-Mouse, Biotin, Clone: GR20, BD

Catalog No. BDB558771 Shop All BD Biosciences Products
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BDB558771 0.1 mg
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Catalog No. BDB558771 Supplier BD Biosciences Supplier No. 558771
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Description

Rat Monoclonal Antibody

The GR20 monoclonal antibody specifically binds to CD119, the α chain of the interferon γ(IFN- γ) receptor. This receptor is expressed by mouse leukocytes, endothelial, and epithelial cells, but not by mature erythrocytes. GR20 mAb recognizes an epitope (susceptible to certain fixatives) in the ligand-binding site of the receptor. It can block the binding of mouse IFN- γ; therefore, it can inhibit IFN- γ.mediated effects including the activation of mouse macrophages for tumor cell killing. IFN- γhas been reported to induce the expression of Ly-6A/E antigen on cell lines and normal B lymphocytes, and the GR20 antibody is capable of inhibiting the IFN- γ

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD119
Applications Flow Cytometry
Classification Monoclonal
Clone GR20
Concentration 0.5mg/mL
Conjugate Biotin
Description Ifngr1; IFN-γ Receptor α; IFN-gamma R alpha; Ifngr; INF-g Receptor; Cd119
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen BALB/c mouse monomyelocytic cell line WEHI-3
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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