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CD119 Rat anti-Mouse, Biotin, Clone: GR20, BD
Rat Monoclonal Antibody
Supplier: BD Biosciences 558771
Description
The GR20 monoclonal antibody specifically binds to CD119, the α chain of the interferon γ(IFN- γ) receptor. This receptor is expressed by mouse leukocytes, endothelial, and epithelial cells, but not by mature erythrocytes. GR20 mAb recognizes an epitope (susceptible to certain fixatives) in the ligand-binding site of the receptor. It can block the binding of mouse IFN- γ; therefore, it can inhibit IFN- γ.mediated effects including the activation of mouse macrophages for tumor cell killing. IFN- γhas been reported to induce the expression of Ly-6A/E antigen on cell lines and normal B lymphocytes, and the GR20 antibody is capable of inhibiting the IFN- γ

Specifications
CD119 | |
Monoclonal | |
0.5mg/mL | |
Ifngr1; IFN-γ Receptor α; IFN-gamma R alpha; Ifngr; INF-g Receptor; Cd119 | |
Rat | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
GR20 | |
Biotin | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
BALB/c mouse monomyelocytic cell line WEHI-3 | |
0.1 mg | |
Immunology | |
Mouse | |
IgG2a κ |
Safety and Handling
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