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Description
The GIR-94 antibody recognizes the extracellular region of the alpha chain subunit (80-95 kDa glycoprotein) of the human interferon- γreceptor (IFN- γR α ; aka, CD119). The functionally active-form of the human IFN- γreceptor consists of two (or more) subunits, with IFN- γR α responsible for IFN- γβ chains required for the transduction of biologic responses. The IFN- γreceptor α chain (CD119) is expressed on the surface of most human cells (except mature erythrocytes) including monocytes, macrophages, T cells, B cells, NK cells, neutrophils, fibroblasts, epithelial cells, and endothelium. The ability of this antibody to bind to IFN- γreceptors of species other than human has not been determined. The immunogen used to generate this hybridoma was human IFN- γR α purified from human placenta. The GIR-94 is a non-neutralizing antibody.
Specifications
Specifications
| Antigen | CD119 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | GIR-94 |
| Concentration | 0.2mg/mL |
| Conjugate | PE |
| Description | IFN-γ Receptor α chain |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human IFN-γRα |
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