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CD11a Mouse anti-Human, NA/LE, Unlabeled, Clone: HI111, BD

Catalog No. BDB555381 Shop All BD Biosciences Products
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BDB555381 0.5 mg
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Catalog No. BDB555381 Supplier BD Biosciences Supplier No. 555381
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Description

Mouse Monoclonal Antibody

Reacts with the 180kDa integrin α chain which associates with CD18 (integrin β2) to form the heterodimer glycoprotein CD11a/CD18. This is known as the lymphocyte function associated antigen-1 (LFA-1), which is on all leukocytes; and is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50). This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11a
Applications Flow Cytometry
Classification Monoclonal
Clone HI111
Concentration 1.0mg/mL
Conjugate Unconjugated
Description LFA-1α; Lymphocyte (Leukocyte) function-associated antigen 1 α chain; ITGAL
Formulation No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Canine, Human, Rabbit
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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