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CD11a Mouse anti-Human, PE, Clone: HI111, BD

Catalog No. BDB555384 Shop All BD Biosciences Products
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Catalog No. BDB555384 Supplier BD Biosciences Supplier No. 555384
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Mouse Monoclonal Antibody

The HI111 monoclonal antibody specifically binds to CD11a, the 180 kDa integrin α chain. This type I transmembrane glycoprotein associates with CD18 (integrin β2) to form the heterodimeric glycoprotein CD11a/CD18. This heterodimer is also known as the lymphocyte (leukocytes) function associated antigen-1 (LFA-1) that is expressed on all leukocytes. LFA-1 is an adhesion molecule involved in lymphocyte and granulocyte functions. LFA-1 mediates adhesion of lymphoid cells to the vascular endothelium in association with its ligand, and the intracellular adhesion molecule-1 (ICAM-1), CD54. Other ligands are ICAM-2 (CD102) and ICAM-3 (CD50).

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11a
Applications Flow Cytometry
Classification Monoclonal
Clone HI111
Conjugate PE
Description LFA-1α; Lymphocyte (Leukocyte) function-associated antigen 1 α chain; ITGAL
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Canine, Human, Rabbit
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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