Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. MilliporeSigma™ anti-CD11b Red Fluor 710, Clone: M1/70,

MilliporeSigma™ anti-CD11b Red Fluor 710, Clone: M1/70,

Catalog No. MABF804MI Shop All MilliporeSigma Products
Change view
Click to view available options
Quantity:
100 μg
25 μg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
MABF804MI 100 μg
MABF803MI 25 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Catalog No. MABF804MI Supplier MilliporeSigma™ Supplier No. MABF804
Add to Cart
Add to Cart

Description

Rat Monoclonal Antibody

Specifically detects CD11b Clone: M1/70 in Human, Mouse samples, and it is validated for Flow Cytometry

The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alphaM (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The M1/70 antibody is widely used as a marker for CD11b expression on mouse macrophages, granulocytes, neutrophils, and NK cells. The antibody is also reported to be cross-reactive for Rhesus macaque CD11b.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11b
Applications Flow Cytometry
Classification Monoclonal
Clone M1/70
Conjugate Red Fluor 710
Formulation Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Accession No. P05555
Gene Symbols Itgam
Host Species Rat
Immunogen Proprietary immunogen
Purification Method Purified by size-exclusion chromatography
Quantity 100 μg
Regulatory Status RUO
Research Discipline Inflammation, Immunology
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Form Purified
Isotype IgG2b κ
Show More Show Less

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.