CD11c Hamster anti-Mouse, APC, Clone: HL3, BD

Hamster Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB561119	BD Biosciences 561119	25 μg
BDB550261	BD Biosciences 550261	0.1 mg

Description

The HL3 antibody reacts with the integrin αx chain of gp150, 95 (CD11c/CD18) which is expressed on dendritic cells and CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and is upregulated on IEL and lymph-node T cells following in vivo activation. CD11c is also found on human NK cells. Although its expression on mouse NK cells is not published, we have detected CD11c on mouse splenic NK cells. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Hamster
Clone: HL3
Isotype: IgG1 λ
Species Reactivity: Mouse
Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes

Flow Cytometry

Specifications

• Antigen: CD11c
• Concentration: 0.2mg/mL
• Classification: Monoclonal
• Host Species: Hamster
• Target Species: Mouse
• Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
• Purification Method: Affinity Purified
• Description: Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4

• Clone: HL3
• Applications: Flow Cytometry
• Conjugate: APC
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.