CD11c Hamster anti-Mouse, BUV395, Clone: HL3, BD

Hamster Monoclonal Antibody

Supplier:  BD Biosciences 564080

Catalog No. BDB564080

Description

The HL3 monoclonal antibody specifically binds to the integrin α x chain of gp150, 95 (CD11c/CD18). CD11c is expressed on dendritic cells, CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and some NK cells. It is upregulated on IEL and lymph-node T cells following in vivo activation. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b.

The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument. With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector. BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

Specifications

• Antigen: CD11c
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4
• Host Species: Hamster
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: HL3
• Conjugate: Brilliant Ultraviolet 395
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.