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CD11c Hamster anti-Mouse, BUV395, Clone: HL3, BD

Catalog No. BDB564080 Shop All BD Biosciences Products
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BDB564080 50 μg
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Catalog No. BDB564080 Supplier BD Biosciences Supplier No. 564080
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Description

Hamster Monoclonal Antibody

The HL3 monoclonal antibody specifically binds to the integrin α x chain of gp150, 95 (CD11c/CD18). CD11c is expressed on dendritic cells, CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and some NK cells. It is upregulated on IEL and lymph-node T cells following in vivo activation. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b.

The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument. With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector. BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11c
Applications Flow Cytometry
Classification Monoclonal
Clone HL3
Concentration 0.2mg/mL
Conjugate Brilliant Ultraviolet 395
Description Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Hamster
Immunogen C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1
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