CD11c Hamster anti-Mouse, BUV395, Clone: HL3, BD
Hamster Monoclonal Antibody
Manufacturer: BD Biosciences 564080
The HL3 monoclonal antibody specifically binds to the integrin α x chain of gp150, 95 (CD11c/CD18). CD11c is expressed on dendritic cells, CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and some NK cells. It is upregulated on IEL and lymph-node T cells following in vivo activation. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b.
The antibody was conjugated to BD Horizon BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument. With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector. BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.
|Brilliant Ultraviolet 395|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4|
|C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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