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CD120a Mouse anti-Human, Unlabeled, Clone: MABTNFR1-B1, BD

Catalog No. BDB550514 Shop All BD Biosciences Products
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Catalog No. BDB550514 Supplier BD Biosciences Supplier No. 550514
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Description

Mouse Monoclonal Antibody

The TNFR1-B1 antibody reacts with the extracellular domain of CD120A which is also known as the 55 kDa receptor for the human cytokines, tumor necrosis factor (TNF) and lymphotoxin-alpha (LT- α ). This receptor is referred to as the p55 or Type I Tumor Necrosis Factor Receptor (TNFRI). TNFRI are expressed by a variety of cell lines, tumor cells, and normal cell types including T cells, monocytes, macrophages, neutrophils, endothelial cells, hepatocytes, chondrocytes, and fibroblasts. Naive B cells express very low or undetectable levels of TNFRI whereas mature erythrocytes and platelets are uniformly negative for TNFRI expression. For the generation of the MABTNFR1-B1 hybridoma, BALB/c mice were immunized with purified, full-length human TNFRI protein that was expressed by insect cells that were infected with a recombinant human TNFRI-baculovirus expression vector. MABTNFR1-B1 specifically binds to natural and recombinant truncated forms of TNFRI.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD120a
Applications Flow Cytometry
Classification Monoclonal
Clone MABTNFR1-B1
Concentration 0.5mg/mL
Conjugate Unconjugated
Description TNF Receptor Type I
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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