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CD125 Rat anti-Mouse, Alexa Fluor 488, Clone: T21, BD
Rat Monoclonal Antibody
Supplier: BD Biosciences 558533
Description
The antibody clone T21 recognizes the mouse α-subunit (also known as CD125) of the IL-5 receptor. The IL-5 receptor is comprised of α- and β-subunits where the α-subunit is specific to the binding of IL-5 ligand and the β-subunit is common among the IL-3, IL5 and granulocyte/macrophage colony-stimulating factor (GM-CSF) receptors. Murine IL-5 belongs to the hematopoietic growth factor family of cytokines and is known to enhance several functions of murine B-cells, including immunoglobulin production, growth and differentiation. Upon binding, T21 inhibits IL-5 induced B-cell proliferation and Ig-secretion.

Specifications
CD125 | |
Monoclonal | |
0.2mg/mL | |
IL-5 Receptor α-subunit | |
Rat | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
T21 | |
Alexa Fluor 488 | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Mouse T88-M | |
0.1 mg | |
Immunology | |
Mouse | |
IgG1 λ |
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