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CD125 Rat anti-Mouse, Alexa Fluor 488, Clone: T21, BD

Catalog No. BDB558533 Shop All BD Biosciences Products
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Catalog No. BDB558533 Supplier BD Biosciences Supplier No. 558533
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Description

Rat Monoclonal Antibody

The antibody clone T21 recognizes the mouse α-subunit (also known as CD125) of the IL-5 receptor. The IL-5 receptor is comprised of α- and β-subunits where the α-subunit is specific to the binding of IL-5 ligand and the β-subunit is common among the IL-3, IL5 and granulocyte/macrophage colony-stimulating factor (GM-CSF) receptors. Murine IL-5 belongs to the hematopoietic growth factor family of cytokines and is known to enhance several functions of murine B-cells, including immunoglobulin production, growth and differentiation. Upon binding, T21 inhibits IL-5 induced B-cell proliferation and Ig-secretion.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD125
Applications Flow Cytometry
Classification Monoclonal
Clone T21
Concentration 0.2mg/mL
Conjugate Alexa Fluor 488
Description IL-5 Receptor α-subunit
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse T88-M
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 λ
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