CD130 Mouse anti-Human, Unlabeled, Clone: AM64, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 555756

Catalog No. BDB555756

Description

The AM64 monoclonal antibody specifically binds to CD130 which is also known as gp130 (Membrane glycoprotein 130), IL6ST (Interleukin-6 signal transducer), and IL6RB/IL-6Rβ (Interleukin-6 Receptor beta). CD130 is a 130 kDa type 1 membrane glycoprotein that belongs to the hemopoietic cytokine receptor superfamily. CD130 serves as a common signaling receptor for several cytokine receptor complexes including those that mediate the biological effects of IL-6, IL-11, IL-27, Cardiotrophin-1 (CT-1), Ciliary neurotrophic factor (CNTF), Leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130 is widely expressed on a variety of cell types including T cells, activated B cells, monocytes, plasma cells, and endothelia. The AM64 antibody can be used in flow cytometry, immunoprecipitation, western blot, and immunohistochemistry on frozen sections.

Specifications

• Antigen: CD130
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: IL6ST; IL6RB; IL-6Rβ; Interleukin-6 Receptor beta; gp130
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: AM64
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Purified Human CD130
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.