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GP130 Mouse anti-Rat, Clone: 745314, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524355

Catalog No. PIMA524355


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Description

Description

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Specifications

Specifications

GP130
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P40190
CD130, CDw130, GP130, GP130-RAPS, IL6R-beta, IL6ST
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
25205
Flow Cytometry, Western Blot
745314
Unconjugated
Il6st
Lyophilized
IL6ST
Mouse myeloma cell line NS0-derived recombit rat gp130 Gln23-Glu618 (predicted)
Protein A/G
RUO
Antibody
Monoclonal
Rat
Documents
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