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Description
Reacts with a type II membrane protein known as 4-1BB ligand. This molecule belongs to the TNF superfamily. It has been reported to have costimulatory function on activated T cells. Reports suggest that stimulation of activated T cells via 4-1BB ligand does not require the presence of other costimulatory molecules, including CD28. Some studies have reported human 4-1BB ligand to be expressed preferentially on primary B cells and B-cell lines. C65-485 antibody is able to react with recombinant human 4-1BB ligand (rh4-1BBL) bound to CD137 (4-1BB receptor) expressed on PHA-stimulated PBMC.
Specifications
Specifications
| Antigen | CD137 Ligand |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | C65-485 |
| Concentration | 0.5mg/mL |
| Conjugate | Unconjugated |
| Description | 4-1BB Ligand |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
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