CD138 Mouse anti-Human, Unlabeled, Clone: DL-101, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 550804

Catalog No. BDB550804

Description

Reacts with CD138 (Syndecan-1), an 85-92 kDa single chain transmembrane protein, expressed on multiple myeloma-derived cell lines and malignant plasma cell populations. It is also expressed on pre-B cells, immature B cells and plasma cells, but not on mature circulating B-lymphocytes. Syndecan-1 is a member of the family of transmembrane heparan sulfate proteoglycans. It is also expressed on some non-hematopoietic cells, including embryonic mesenchymal cells, vascular smooth muscle cells, endothelial and neural cells. CD138 binds to many extracellular matrix proteins through its heparan sulfate side-chains, like fibronectin, collagen types I, III and V, tenascin, thrombospondin, and antithrombin III. It is considered an extracellular matrix receptor that may serve as a co-receptor for fibroblast growth factor and related molecules. Monoclonal antibody DL-101 does not block the binding of clone B-B4 (another anti-syndecan-1 antibody) or Mi15 by flow cytometric analysis.

Specifications

• Antigen: CD138
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: Syndecan-1
• Host Species: Mouse
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: DL-101
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

For Research Use Only.