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Description
The MφP9 monoclonal antibody specifically binds to human CD14, a 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored and single chain glycoprotein expressed at high levels on monocytes. Additionally, this CD14-specific antibody reacts with interfollicular macrophages, reticular dendritic cells and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB. The purified antibody is suitable for staining acetone-fixed, frozen tissue sections.
This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20-nm filter).
Specifications
Specifications
| Antigen | CD14 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | MφP9 |
| Conjugate | PE-CF594 |
| Description | LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human monocytes |
| Purification Method | Affinity Purified |
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For Research Use Only.
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