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CD14 Mouse anti-Human, PE, Clone: M5E2, BD

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Catalog No. BDB557154 Supplier BD Biosciences Supplier No. 557154
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Description

Mouse Monoclonal Antibody

The M5E2 monoclonal antibody specifically binds to CD14, a 53–55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein expressed at high levels on monocytes. Additionally, the anti-CD14 antibody reacts with interfollicular macrophages, reticular dendritic cells, and some Langerhans cells. CD14 has been identified as a high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS) and serum LPS-binding protein, LPB.

This clone also cross-reacts with a major subset of peripheral blood monocytes on both rhesus and cynomolgus macaque monkeys. The pattern of reactivity on monocytes is weaker than that observed with peripheral blood monocytes from normal human donors. M5E2 reacts on non-human primate granulocytes and not on human granulocytes.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD14
Applications Flow Cytometry
Classification Monoclonal
Clone M5E2
Conjugate PE
Description LPS receptor; LPS-R; Myeloid cell-specific leucine-rich glycoprotein
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human CD14 Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Cynomolgus, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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