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CD144 Rat anti-Mouse, Alexa Fluor 647, Clone: 11D4.1, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 562242

Catalog No. BDB562242


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Description

Description

The 11D4.1 antibody monoclonal antibody specifically binds to mouse CD144, also known as VE-cadherin. CD144 is a type I transmembrane protein and is a member of the cadherin superfamily. VE-cadherin is an endothelial cell-specific, homophilic adhesion molecule. It is concentrated at interendothelial cells contacts and is thought to be involved in the maintenance of cell layer integrity. In vitro and in vivo studies indicate that the 11D.4 mAb interferes with VE-cadherin-mediated intercellular adhesion.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD144
Monoclonal
0.2mg/mL
Cdh5; Cadherin-5; CADH5; VE-cadherin; Vascular endothelial cadherin; 7B4
Rat
Affinity Purified
RUO
Mouse
IgG2a κ
Flow Cytometry
11D4.1
Alexa Fluor 647
Aqueous buffered solution containing ≤0.09% sodium azide.
Mouse VE-Cadherin-Ig Fusion
50 μg
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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