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Description
The 11D4.1 antibody monoclonal antibody specifically binds to mouse CD144, also known as VE-cadherin. CD144 is a type I transmembrane protein and is a member of the cadherin superfamily. VE-cadherin is an endothelial cell-specific, homophilic adhesion molecule. It is concentrated at interendothelial cells contacts and is thought to be involved in the maintenance of cell layer integrity. In vitro and in vivo studies indicate that the 11D.4 mAb interferes with VE-cadherin-mediated intercellular adhesion.
Specifications
Specifications
| Antigen | CD144 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 11D4.1 |
| Concentration | 0.2mg/mL |
| Conjugate | PE |
| Description | Cdh5; Cadherin-5; CADH5; VE-cadherin; Vascular endothelial cadherin; 7B4 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse VE-Cadherin-Ig Fusion |
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