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CD15 Mouse anti-Human, Unlabeled, Clone: W6D3, BD

Catalog No. BDB557895 Shop All BD Biosciences Products
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0.1mg; Unlabeled
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BDB557895 0.1mg; Unlabeled
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Catalog No. BDB557895 Supplier BD Biosciences Supplier No. 557895
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Description

Mouse Monoclonal Antibody

The W6D3 monoclonal antibody specifically binds to 3-fucosyl-N-acetyllactosamine (3-FAL), a 220 kDa carbohydrate structure, also called X-hapten. 3-FAL is expressed on >95% of granulocytes, including neutrophils and eosinophils, and on monocytes to a varying degree, but not on lymphocytes or basophils. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis. Most CD15 antibodies are IgM isotype; clone W6D3 is a mouse IgG1 isotype. In comparison studies with clone HI98, a known CD15 antibody, clone W6D3 shows brighter fluorescence staining and its binding can be blocked by clone HI98.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

For Research Use Only.

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