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CD152 Mouse anti-Human, Unlabeled, Clone: BNI3, BD

Catalog No. BDB555851 Shop All BD Biosciences Products
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BDB555851 0.1 mg
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Catalog No. BDB555851 Supplier BD Biosciences Supplier No. 555851
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Description

Mouse Monoclonal Antibody

Reacts with the “cytolytic T lymphocyte-associated antigen”, CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells, suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 enhances T-cell proliferation induced by CD3 and CD28. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD152
Applications Flow Cytometry
Classification Monoclonal
Clone BNI3
Concentration 0.5mg/mL
Conjugate Unconjugated
Description CTLA-4; AILIM; Cytotoxic T-lymphocyte protein 4
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human CTLA4 Recombinant Protein
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG2a κ
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For Research Use Only.

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