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CD154 Mouse anti-Human, NA/LE, Unlabeled, Clone: HCD40L-M90.1, BD

Catalog No. BDB552559 Shop All BD Biosciences Products
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Catalog No. BDB552559 Supplier BD Biosciences Supplier No. 552559
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Description

Mouse Monoclonal Antibody

Clone hCD40L-M90.1 reacts with CD40 ligand (CD40L), a 39 kDa type II membrane glycoprotein expressed on activated T cells. CD40-CD40L interaction plays a very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation. In addition, blocking of CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching. It has been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that encodes CD40L.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD154
Applications ELISA
Classification Monoclonal
Clone HCD40L-M90.1
Concentration 0.5mg/mL
Conjugate Unconjugated
Description CD40L
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.

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