CD158a Mouse anti-Human, APC, Clone: HP-3E4, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 564319
The HP-3E4 monoclonal antibody recognizes CD158a. CD158a is a 58 kDa membrane glycoprotein, member of the killer-inhibitory receptor (KIR). The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on <1-8% of NK cells and a subset of T cells which are involved in recognition of MHC class I molecules on target cells and inhibit cytotoxicity. CD158a is an antigen which recognizes HLA-C molecules (-Cw*0401 and -Cw*1503). This antibody is suitable for staining acetone-fixed, frozen tissue sections. It was reported that this clone also crossreacted with NKAT8 (CD158i) transfected cells.
|KIR2DL1; KI2L1; NKAT; NKAT-1; NKAT1; KIR-K64; KIR221; p58.1|
|Human NK Cells|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.|
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