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  6. CD16 Mouse anti-Human, Brilliant Violet 421, Clone: 3G8, BD

CD16 Mouse anti-Human, Brilliant Violet 421, Clone: 3G8, BD

Catalog No. BDB562878 Shop All BD Biosciences Products
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BDB562874 100 Tests
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Description

Mouse Monoclonal Antibody

The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcγRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue™ conjugates.

Host Species: Mouse
Clone: 3G8
Isotype: IgG1, κ
Species Reactivity: Hu
Immunogen: Human polymorphonuclear leukocytes

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD16
Applications Flow Cytometry
Classification Monoclonal
Clone 3G8
Conjugate Brilliant Violet 421
Description FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human polymorphonuclear leukocytes
Purification Method Affinity Purified
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Baboon, Cynomolgus, Human, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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