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Description
Reacts with the 50-65kDa transmembrane form of IgG Fc (FcγRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. CD16 antibody blocks the binding of soluble immune complexes to granulocytes. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Host Species: Mouse
Clone: 3G8
Isotype: IgG1 κ
Species Reactivity: Human
Flow Cytometry
Specifications
Specifications
| Antigen | CD16 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 3G8 |
| Conjugate | PE-Cyanine7 |
| Description | FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human polymorphonuclear leukocytes |
| Purification Method | Affinity Purified |
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For Research Use Only.
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