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  6. CD16 Mouse anti-Human, V450, Clone: 3G8, BD

CD16 Mouse anti-Human, V450, Clone: 3G8, BD

Catalog No. BDB560475 Shop All BD Biosciences Products
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BDB560475 30 Tests
BDB560474 120 Tests
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Catalog No. BDB560475 Supplier BD Biosciences Supplier No. 560475
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Description

Mouse Monoclonal Antibody

Reacts with the 50-65kDa transmembrane form of IgG Fc Receptor (FcγRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.

Host Species: Mouse
Clone: 3G8
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Human polymorphonuclear leukocytes

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD16
Applications Flow Cytometry
Classification Monoclonal
Clone 3G8
Conjugate Violet Fluor 450 (V450)
Description FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3
Formulation Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human polymorphonuclear leukocytes
Purification Method Affinity Purified
Quantity 30 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Baboon, Cynomolgus, Human, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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