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CD160 Rat anti-Mouse, Alexa Fluor 647, Clone: CNX46-3, BD

Catalog No. BDB562217 Shop All BD Biosciences Products
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BDB562217 0.1 mg
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Catalog No. BDB562217 Supplier BD Biosciences Supplier No. 562217

Description

Rat Monoclonal Antibody

The CNX46-3 monoclonal antibody specifically binds to mouse CD160, also known as Natural Killer Cell Receptor BY55. CD160 is a glycosyolphosphatidylinositol-anchored membrane glycoprotein that contains a single Ig domain. This member of the Ig Superfamily was the first identified as a MHC Class I antigen-specific Ig-like Receptor that was expressed by mouse NK cells. As a receptor, CD160 can bind to classical and non-classical MHC class I molecules with low affinity. As a ligand, CD160 can bind to HVEM (Herpes Virus Entry Mediator, a TNF Receptor Family Member). CD160 is expressed on a subset of NK cells, NKT cells, activated CD8+ T cells and TCR γδ T cells. The functions of CD160 have been reported to regulate NK cell activation both positively and negatively, depending on the stimulus.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD160
Applications Flow Cytometry
Classification Monoclonal
Clone CNX46-3
Concentration 0.2mg/mL
Conjugate Alexa Fluor 647
Description Cd160; By55; Natural killer cell receptor BY55
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse CD160 Recombinant Protein
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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