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Description
The 3A6 monoclonal antibody specifically binds to the activated leukocyte cell adhesion molecule (ALCAM), a 100-105 kDa transmembrane glycoprotein, also known as the CD6 ligand, CD166. It is composed of an immunoglobulin-like extracellular domain, a transmembrane region and a short cytoplasmic tail. ALCAM belongs to the Ig superfamily of proteins and is expressed on neurons, activated T cells, activated monocytes, epithelial cells and fibroblasts. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T-cell development.
The antibody was conjugated to BD Horizon BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).
Specifications
Specifications
| Antigen | CD166 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 3A6 |
| Conjugate | Brilliant Violet 786 |
| Description | ALCAM; Activated leucocyte cell adhesion molecule; MEMD |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide |
| Host Species | Mouse |
| Purification Method | Affinity Purified |
| Quantity | 50 Tests |
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