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CD166 Mouse anti-Human, Brilliant Violet 786, Clone: 3A6, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 564939

Catalog No. BDB564939

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The 3A6 monoclonal antibody specifically binds to the activated leukocyte cell adhesion molecule (ALCAM), a 100-105 kDa transmembrane glycoprotein, also known as the CD6 ligand, CD166. It is composed of an immunoglobulin-like extracellular domain, a transmembrane region and a short cytoplasmic tail. ALCAM belongs to the Ig superfamily of proteins and is expressed on neurons, activated T cells, activated monocytes, epithelial cells and fibroblasts. CD166 plays an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T-cell development.

The antibody was conjugated to BD Horizon BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).



ALCAM; Activated leucocyte cell adhesion molecule; MEMD
Affinity purified
IgG1, κ
Flow Cytometry
Brilliant Violet 786
Aqueous buffered solution containing BSA and ≤0.09% sodium azide
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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