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CD172a Rat anti-Mouse, Unlabeled, Clone: P84, BD
Rat Monoclonal Antibody
Supplier: BD Biosciences 552371
Description
The P84 antibody reacts with CD172a, also known as SIgnal-Regulatory Protein α (SIRPα), Src Homology 2 domain-containing protein tyrosine Phosphatase (SHP) Substrate 1 (SHPS-1), or Brain Immunoglobulin-like molecule with Tyrosine-based activation motifs (BIT). CD172a is an adhesion molecule of the Ig superfamily which is expressed on neurons in the central nervous system and the retina, on macrophages, and on bone-marrow myeloid cells. Its ligand, CD47, or Integrin-Associated Protein (IAP), is expressed by a wide variety of cells. CD172a and CD47 are proposed to mediate bi-directional signaling to modify neural synaptic activity and regulate the phagocytic activities of macrophages.

Specifications
CD172a | |
Monoclonal | |
0.5mg/mL | |
SIRPα, SHPS-1, BIT | |
Rat | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C |
Flow Cytometry | |
P84 | |
Unconjugated | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Membrane fractions from mouse brain | |
0.1 mg | |
Immunology | |
Mouse | |
IgG1 κ |
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