CD184 Mouse anti-Human, PE-Cy5, Clone: 12G5, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 555975

Catalog No. BDB555975

Description

Reacts with fusin (CXCR4), a seven-transmembrane domain, G-protein-linked glycoprotein. Fusin is expressed on a wide variety of CD4+ and CD4- cells including those from spleen, brain and lung. It has been shown to function as a cofactor for infection with T-cell tropic strains of HIV-1 and also as a receptor for CD4-independent infection. 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.

Host Species: Mouse
Clone: 12G5
Isotype: IgG2a κ
Species Reactivity: Human

Flow Cytometry

Specifications

• Antigen: CD184
• Classification: Monoclonal
• Conjugate: PE-Cyanine5
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: SIVmac variant CP-MAC-infected Sup-T1 cells
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Flow Cytometry
• Clone: 12G5
• Description: CXCR4; Fusin; SDF-1 receptor; LAP3; LCR1; LESTR; NPYY3R; NPY3R; WHIM; HM89
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.